Graves' Disease\r\nGraves' disease is an autoimmune disorder that is a considerable cause of Hyperthyroidism. The types of autoimmune disease occur from unspecified causes but most of the responsible causes come from family histories such as Genetically and some of the environmental factors are also responsible for it.\u00a0Graves' disease is also a type of problem in which release form of antibodies commonly called thyroid stimulating immunoglobulins also TSIs, attack thyroid cell receptors. Thyroid stimulating immunoglobulins enable thyroid cell receptors to send signals to TSH which is called thyroid stimulating hormones who then releases thyroid hormones both T3 and T4. The level of TSH falls down as the level of T3 and T4 overcome and cause hyperthyroidism.\u00a0There are also other many causes of hyperthyroidism but Graves' disease is considered as a common cause.\r\n\r\nWho Can Be Affected by\u00a0Graves' Disease?\r\nGraves' disease main causes are unknown but genetic and environmental factors define it. Further, other factors that can be responsible are:\r\n\r\nProgression in stress, infection or giving birth.\r\nAlready have an autoimmune disease such as Rheumatoid Arthritis and Type I Diabetes.\r\nSmoking can increase the risk.\r\nSymptoms of\u00a0Graves' Disease\r\nSymptoms of Graves' disease are:\r\n\r\nGoiter\r\nExcessive Sweating\r\nHeat intolerance\r\nIncreased appetite\r\nWeight reduction\r\nShaking hands\r\nTremors\r\nDiarrhea\r\nDefecation\r\nHypertension\r\nRapid heartbeat\r\nAnxiety, Depression\r\nInsomnia\r\nHair loss\r\nVision problem\r\nErectile dysfunction or libido\r\nMenstrual changes\r\nDiagnosis of\u00a0Graves' Disease\r\nDiagnosis of Graves' disease depends upon different factors:\r\n\r\nPhysical Exam\r\nThis is the first step to consider patients for next test for Graves' disease. The physical exam includes:\r\n\r\nEyes problem\r\nThyroid gland enlargement,\u00a0Goiter\r\nSwelling or inflammation\r\nWeight loss\r\nSkin color\r\nThought, speech, Behavior\r\nTremors, weakness of muscles\r\nHair texture\r\nOnycholysis\r\nRapid heart rate or overactive heart\r\nLaboratory Test\r\nTSH LEVEL TESTING\r\nThis test is used to check the level of TSH to determine the amount of T3 and T4 hormones.\u00a0TSH is thyroid stimulating hormones released from the pituitary gland and helps the thyroid to produce T3 and T4 hormones.\u00a0Testing will show the low level of TSH while the increase of T3 and T4 hormones. Sometimes this test is not sufficient for doctors to identify the disease type.\r\n\r\nT3 AND T4 TEST\r\nThis test used to identify the exact level of these two thyroid hormones in the blood. T3 is triiodothyronine and T4 is thyroxine, two hormones whose increase level is a main cause of hyperthyroidism.\u00a0T3 and T4 hormones are needed in our body to regulate the cellular metabolism such as body temperature, heart rate, and metabolism. Diagnosis depends upon the abnormal level of these two hormones in test reports.\r\n\r\nRADIOACTIVE IODINE UPTAKE\r\nIn this test, an iodine pill is given to the patient to check the functioning of the thyroid gland or how thyroid gland act after receiving iodine. After the 6-7 hrs. of swallowing of a pill, the test is performed with the help of scan. This test will determine whether hyperthyroid is due to Graves' disease or others factors are responsible.\r\n\r\nULTRASOUND AND X-RAY\r\nThis test is specially performed in a person who can't take radioactive iodine uptake and those pregnant women. High-frequency sound waves will pass from inside our body to check the enlargement or structure of the thyroid gland.\u00a0X-ray, MRI, CT scan are some imaging tests to check the presence of Graves' disease and those clinically failed assessments.\r\n\r\nTreatments of\u00a0Graves' Disease\r\nGraves' disease is a cause of hyperthyroidism so the treatments start to control over production of thyroid hormones. Some treatments are:\r\n\r\nAnti-thyroid Medications\r\nAntithyroid medication inhibits the release of an excess amount of thyroid form thyroid gland. There are two types of medicine for hyperthyroidism used\r\n\r\nPropylthiouracil (PTU)\r\nMethimazole (Tapazole)\r\nSide effects of these medicines include skin rashes, itching, hives, heartburn, metallic taste, nausea, vomiting and pain in joints and muscles. In pregnant women, selection of medicine is important and most of the time doctor can suggest the use of PTU instead of Methimazole in pregnancy.\r\n\r\nRadioactive Iodine (RAI)\r\nThis treatment is not good for pregnant women or in breastfeeding. In some cases medicines cannot show their affection, RAI is preferred.\u00a0It is an iodine pill given in hyperthyroid condition or Graves' disease and acts on thyroid cells to destroy them. It is safe as picked up by thyroid cells and destruction is normal that no widespread side effects.\r\n\r\nSurgery\r\nSurgery is recommended in those who can not tolerate antithyroid medicines and if you are pregnant so you can not take medicine, surgery is preferred.\u00a0It is the type of thyroidectomy to remove the enlargement of the thyroid gland and thus the excess production of thyroid hormones. This type of surgery also included in nodular thyroid goiter. Surgery can pose a small risk on the vocal cord and parathyroid glands.\u00a0Each given treatments have their own risk and benefits which depend upon your types of symptoms and severity of disease that you have.